All AbMole products are for research use only, cannot be used for human consumption.
Nicotinamide is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins. Nicotinamide plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions.
J Tradit Complement Med. 2025 Feb 07.
Huang-qin decoction increases the sensitivity of EGFR-TKIs to NSCLC cells by regulating stat3/GPX4 to induce redox ratio and ROS to inhibit CSCs
Nicotinamide purchased from AbMole
Patent. CN119639678A 2025 Mar 18.
Patent. CN119639678A
Nicotinamide purchased from AbMole
Cancer Lett. 2024 Oct 02;605:217284.
Exploring epigenetic dynamics unveils a super-enhancer-mediated NDRG1-β-catenin axis in modulating gemcitabine resistance in pancreatic cancer
Nicotinamide purchased from AbMole
FEBS J. 2024 Sep 09.
MOF-mediated acetylation of CDK9 promotes global transcription by modulating P-TEFb complex formation
Nicotinamide purchased from AbMole
J Cancer. 2024 Jun 22.
Tanreqing injection inhibits stemness and enhances sensitivity of non-small cell lung cancer models to gefitinib through ROS/STAT3 signaling pathway
Nicotinamide purchased from AbMole
Patent. CN114606192A 2023-08-08.
Patent. CN114606192A
Nicotinamide purchased from AbMole
Patent. CN114606192A 2023 Aug 08; .
Patent. CN114606192A
Nicotinamide purchased from AbMole
Cell Stem Cell. 2020 Nov 5;27(5):840-851.e6.
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo
Nicotinamide purchased from AbMole
Sci Rep. 2020 Jul 31;10(1):12991.
Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis
Nicotinamide purchased from AbMole
| Molecular Weight | 122.12 |
| Formula | C6H6N2O |
| CAS Number | 98-92-0 |
| Solubility (25°C) | DMSO 30 mg/mL Water 30 mg/mL |
| Storage | -20°C, protect from light, sealed |
[1] Mario Mehmel, et al. Nicotinamide Riboside-The Current State of Research and Therapeutic Uses
[3] Luca Fania, et al. Role of Nicotinamide in Genomic Stability and Skin Cancer Chemoprevention
[5] Frances M Walocko, et al. The role of nicotinamide in acne treatment
| Related Sirtuin Products |
|---|
| Selisistat
Selisistat (EX 527) is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor with an IC50 of 98 nM. |
| SRT1720 Hydrochloride
SRT1720 Hydrochloride is a selective small molecule activator of SIRT1 that is 1,000-fold more potent than resveratrol (EC1.5 = 0.16 versus 46.2 µM, respectively). SRT1720 increased the activity of SIRT1 and AMPKα phosphorylation at Ser485 via the cAMP-protein kinase A (PKA) pathway. |
| Resveratrol
Resveratrol is a phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. |
| Balsalazide disodium
Balsalazide is an anti-inflammatory compound used to study inflammatory bowel disease and ulcerative colitis. |
| Sirtinol
Sirtinol is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM, respectively. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
