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NFPS

Cat. No. M7025

All AbMole products are for research use only, cannot be used for human consumption.

NFPS Structure

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Quality Control & Documentation
Biological Activity

NFPS is a selective, non-transportable inhibitor of GlyT1 which displays no activity at GABA or glutamate receptors (IC50 values are 2.8, 9.8 and 56000 nM for hGlyT1, rGlyT1 and rGlyT2 respectively). Enhances the amplitude of the NMDA component of glutamatergic EPSCs.

Chemical Information
Molecular Weight 393.45
Formula C24H24FNO3
CAS Number 405225-21-0
Solubility (25°C) DMSO 3.93 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Gavathiotis, et al. Nat Chem Biol. Direct and selective small-molecule activation of proapoptotic BAX.

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Keywords: NFPS supplier, inhibitors, activators

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