Free shipping on all orders over $ 500

NF340 

Cat. No. M29114

All AbMole products are for research use only, cannot be used for human consumption.

NF340  Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research.

Chemical Information
Molecular Weight 986.84
Formula C37H26N4Na4O15S4
CAS Number 202982-98-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Georg Gruenbacher, et al. Br J Pharmacol. The human G protein-coupled ATP receptor P2Y11 is a target for anti-inflammatory strategies

[2] Feng Gao, et al. IUBMB Life. P2Y11 receptor antagonist NF340 ameliorates inflammation in human fibroblast-like synoviocytes: An implication in rheumatoid arthritis

[3] Tingting Zhang, et al. ChemistryOpen. Sulfonated Compounds Bind with Prostatic Acid Phosphatase (PAP248-286) to Inhibit the Formation of Amyloid Fibrils

[4] Charles Kennedy. Adv Exp Med Biol. P2Y11 Receptors: Properties, Distribution and Functions

[5] Karin Dreisig, et al. Purinergic Signal. A critical look at the function of the P2Y11 receptor

Related P2 Receptor Products
Prasugrel hydrochloride

Prasugrel hydrochloride is a novel inhibitor of platelet activation and aggregation.

GW 791343 dihydrochloride

GW 791343 dihydrochloride is a non-competitive inhibitor of human P2X(7) receptor.

Prasugrel

Prasugrel is a platelet inhibitor irreversibly binding to P2Y12 receptors.

MRS 2578

MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.

PPADS Tetrasodium

PPADS tetrasodium salt is a non-selective P2 purinergic antagonist blocking recombinant P2X1, P2X2, P2X3, P2X5 with IC50 of 1-2.6 μM, native P2Y2-like with IC50 of ~ 0.9 mM, and recombinant P2Y4 receptors with IC50 of ~ 15 mM

  Catalog
Abmole Inhibitor Catalog




Keywords: NF340  supplier, P2 Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.