All AbMole products are for research use only, cannot be used for human consumption.
Nevirapine (NSC 641530) is a potent, specific non-nucleoside reverse transcriptase inhibitor (NNRTIs) that non-competitively inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with a Ki of 220 nM. Nevirapine (NSC 641530) can be used in AIDS-related researchs.
| Molecular Weight | 266.3 |
| Formula | C15H14N4O |
| CAS Number | 129618-40-2 |
| Solubility (25°C) | DMSO 15 mg/mL (Need ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] J-J Parienti, et al. Nevirapine and cardiovascular risk
[3] M Popovic, et al. Nevirapine hypersensitivity
[4] Ana Milinkovic, et al. Nevirapine in the treatment of HIV
[5] M Mirochnick, et al. Nevirapine: pharmacokinetic considerations in children and pregnant women
| Related Reverse Transcriptase Products |
|---|
| Stavudine
Stavudine (D4T) is a potent inhibitor of HIV-1 reverse transcriptase in vitro. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis. |
| Abacavir sulfate
Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1. |
| Dapivirine
Dapivirine is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations. |
| Etravirine
Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. |
| Rilpivirine (R278474)
Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
