Free shipping on all orders over $ 500

Nefazodone hydrochloride

Cat. No. M5809

All AbMole products are for research use only, cannot be used for human consumption.

Nefazodone hydrochloride Structure
Synonym:

BMY-13754; MJ-13754-1

Size Price Availability Quantity
10mM*1mL in DMSO USD 70 In stock
5mg USD 40 In stock
10mg USD 65 In stock
25mg USD 127 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A (Ki=5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake (IC50 of 290 and 300 nM, respectively).

Chemical Information
Molecular Weight 506.47
Formula C25H33Cl2N5O2
CAS Number 82752-99-6
Solubility (25°C) DMSO 35 mg/mL
Water ~1 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shin DS, et al. Toxicol Appl Pharmacol. A novel assessment of nefazodone-induced hERG inhibition by electrophysiological and stereochemical method.

Related 5-HT Receptor Products
Granisetron hydrochloride

Granisetron hydrochloride is a potent and selective 5-HT3 receptor antagonist that possesses potent antiemetic activity.

Sumatriptan succinate

Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache.

Vortioxetine hydrobromide

Vortioxetine hydrobromide (Lu AA21004) is a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist, a 5-HT1B receptor partial agonist, a 5-HT1A receptor agonist and a 5-HT transporter (5-HTT) inhibitor in vitro.

Prucalopride

Prucalopride is a potent, selective and specific serotonin 5-HT4 receptor agonist with enterokinetic properties.

(1S-cis)-Milnacipran Hydrochloride

(1S-cis)-Milnacipran hydrochloride is a selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.

  Catalog
Abmole Inhibitor Catalog




Keywords: Nefazodone hydrochloride, BMY-13754; MJ-13754-1 supplier, 5-HT Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.