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ND-336 is a selective inhibitor of matrix metalloproteinase (MMP)-2, MMP-9, and MMP-14, with Kis of 85, 150, and 120 nM, respectively. ND-336 accelerates diabetic wound healing in mice by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.
| Molecular Weight | 371.9 |
| Formula | C16H18ClNO3S2 |
| CAS Number | 1807453-83-3 |
| Form | Solid |
| Storage | Powder -20°C |
[3] Mayland Chang, et al. Acc Chem Res. Strategy for Treatment of Infected Diabetic Foot Ulcers
[4] Jeffrey I Jones, et al. Pharmaceuticals (Basel). Targeting MMP-9 in Diabetic Foot Ulcers
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