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NCX 4016

Cat. No. M8606

All AbMole products are for research use only, cannot be used for human consumption.

NCX 4016 Structure

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Quality Control & Documentation
Biological Activity

NCX 4016 (nitroaspirin) is nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor. NCX 4016 improves postischemic ventricular dysfunction and to reduce myocardial infarct size in rabbit.

Chemical Information
Molecular Weight 331.28
Formula C16H13NO7
CAS Number 175033-36-0
Solubility (25°C) DMSO: 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Narasimham L Parinandi, et al. Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells

[2] Paolo Gresele, et al. Pharmacologic profile and therapeutic potential of NCX 4016, a nitric oxide-releasing aspirin, for cardiovascular disorders

[3] Nirmal S Mann. No-Aspirin (NCX 4016)

[4] Mario Di Napoli, et al. NCX-4016 NicOx

[5] Stefano Fiorucci, et al. NCX-4016 (NO-aspirin) inhibits lipopolysaccharide-induced tissue factor expression in vivo: role of nitric oxide

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Keywords: NCX 4016 supplier, inhibitors, activators

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