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NB001

Cat. No. M8218

All AbMole products are for research use only, cannot be used for human consumption.

NB001 Structure

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Quality Control & Documentation
Biological Activity

NB001, originally believed to be a selective inhibitor of adenylyl cyclase 1 (AC1), new evidence suggests NB001 does not interact with AC1 directly. NB001 may reduce cAMP accumulation in cells through an unknown mechanism that is dependent on AC1.

Chemical Information
Molecular Weight 264.33
Formula C12H20N6O
CAS Number 686301-48-4
Solubility (25°C) Water: ≥24 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ren-Hao Liu, et al. Selective inhibition of adenylyl cyclase subtype 1 reduces inflammatory pain in chicken of gouty arthritis

[2] Wen-Bo Kang, et al. Analgesic effects of adenylyl cyclase inhibitor NB001 on bone cancer pain in a mouse model

[3] Zhen Tian, et al. Analgesic effects of NB001 on mouse models of arthralgia

[4] Ming-Ming Zhang, et al. Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain

[5] Mingtang Li, et al. Isolation of nitrobenzene degrading strain Pseudomonas NB001 and application in the bioremediation of polluted water body

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Keywords: NB001 supplier, inhibitors, activators

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