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NAV 26

Cat. No. M7018

All AbMole products are for research use only, cannot be used for human consumption.

NAV 26 Structure

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Quality Control & Documentation
Biological Activity

NAV 26 is a selective Nav1.7 channel blocker (IC50 = 370 nM). Exhibits >85-fold selectivity for Nav1.7 over Nav1.5 and hERG channels. Reduces nociceptive behavior in rat models of pain.

Chemical Information
Molecular Weight 434.41
Formula C22H21F3N2O4
CAS Number 1198160-14-3
Solubility (25°C) DMSO 43.44 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sasazawa, et al. ACS Chem Biol. Xanthohumol impairs autophagosome maturation through direct inhibition of valosin-containing protein.

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Keywords: NAV 26 supplier, inhibitors, activators

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