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Natamycin

Cat. No. M1958

All AbMole products are for research use only, cannot be used for human consumption.

Natamycin Structure
Synonym:

Natacyn; Pimaricin

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
25mg USD 40 In stock
50mg USD 55 In stock
100mg USD 90 In stock
200mg USD 160 In stock
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Quality Control & Documentation
Biological Activity

Natamycin (also known as Pimaricin, Natacyn) is a naturally occurring antifungal agent. In the bioautographic study, the antibiotic activity of natamycin was restricted to the gastrointestinal tract and lasted less than 24 h. Natamycin is used to treat fungal infections, including Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium. Natamycin shows negligible absorption into the body when administered in these ways. However, unlike nysatin and filipin, Natamycin (Pimaricin) does not change the permeability of the plasma membrane. Natamycin was found to be effective in fungal keratitis, similar to Natacyn, and it can stop the corner vascularisation, iritis, hypopyon and macular nebula to happen.

Chemical Information
Molecular Weight 665.73
Formula C33H47NO13
CAS Number 7681-93-8
Solubility (25°C) DMSO 9 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Dong XH, et al. Int J Ophthalmol. Antifungal efficacy of natamycin in experimental fusarium solani keratitis.

[2] Bhatta RS, et al. Int J Pharm. Mucoadhesive nanoparticles for prolonged ocular delivery of natamycin: In vitro and pharmacokinetics studies.

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Keywords: Natamycin, Natacyn; Pimaricin supplier, Antibiotic, inhibitors, activators

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