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NAMI-A

Cat. No. M8782

All AbMole products are for research use only, cannot be used for human consumption.

NAMI-A Structure

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Quality Control & Documentation
Biological Activity

Nami-a is an effective anti-metastasis compound in vivo and has little cytotoxicity to many cancer cells. Anti-metastasis NAMI-A is attributed to the formation of adducts with membrane and cytoplasmic proteins. However, namI-A induces potent and selective cytotoxicity in several leukemia cell lines. Nami-a has low toxicity to host tissue.

Chemical Information
Molecular Weight 458.18
Formula C5H10Cl4N2ORuS · C3H5N2
CAS Number 201653-76-1
Solubility (25°C) Water: 2 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] COVIDSurg Collaborative, et al. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study

[2] Dinesh Khanna, et al. Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial

[3] Enzo Alessio, et al. NAMI-A and KP1019/1339, Two Iconic Ruthenium Anticancer Drug Candidates Face-to-Face: A Case Story in Medicinal Inorganic Chemistry

[4] Enzo Alessio, et al. The Deceptively Similar Ruthenium(III) Drug Candidates KP1019 and NAMI-A Have Different Actions. What Did We Learn in the Past 30 Years?

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Keywords: NAMI-A supplier, inhibitors, activators

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