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Naltrindole hydrochloride is a highly selective non-peptide δ opioid antagonist (Ki = 0.02-0.3 nM), showing 223- and 346-fold greater activity at δ than at μ and κ opioid receptors. Naltrindole hydrochloride can cross the blood-brain barrier.
Biochem Biophys Res Commun. 2026 Feb 07;806:153411.
SLL-023ACP, a KOR/MOR dual agonist, produces potent antinociception with fewer side effects
Naltrindole hydrochloride purchased from AbMole
| Molecular Weight | 450.96 |
| Formula | C26H26N2O3.HCl |
| CAS Number | 111469-81-9 |
| Solubility (25°C) | DMSO 5 mg/mL Ethanol 5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Opioid Receptor Products |
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| ADL5859 Hydrochloride
ADL5859 is a potent, selective and orally bioavailable δ-opioid receptor agonist (Ki = 0.84 nM, EC50 = 20 nM). |
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JTC-801 is a novel opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM. |
| Meptazinol hydrochloride
Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]dihydromorphine binding with IC50 of 58 nM. |
| Nalmefene hydrochloride
Nalmefene is an opioid receptor antagonist, it is used primarily in the management of alcohol dependence. |
| Naloxone hydrochloride
Naloxone hydrochloride is an opioid inverse agonist compound used to counter the effects of opiate overdose. |
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