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Nalidixic acid

Cat. No. M3249

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Nalidixic acid Structure
Size Price Availability Quantity
1g USD 40 In stock
5g USD 60 In stock
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Quality Control & Documentation
Biological Activity

Nalidixic acid (NegGram) is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase. Evidence exists that the active metabolite, hydroxynalidixic acid, binds strongly, but reversibly, to DNA, interfering with synthesis of RNA and, consequently, with protein synthesis.

Chemical Information
Molecular Weight 232.24
Formula C12H12N2O3
CAS Number 389-08-2
Form Solid
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] R R Bailey, et al. Nalidixic acid arthralgia

[2] G Pagnini. Nalidixic acid

[3] H H Zinsser. Nalidixic acid in acute and chronic urinary tract infections

[4] H Singh, et al. Nalidixic acid

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Keywords: Nalidixic acid supplier, Antibiotic, inhibitors, activators

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