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Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel. Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel, in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability. Nab-Paclitaxel displays less toxicity and greater antitumor activity.
Nab-Paclitaxel (30-50 mg/kg, i.v., administer on day 1, 8, 15) significantly inhibits RH4 tumor growth with tumor regression after second dosage on day 8 in mice bearing rhabdomyosarcoma (RH4 and RD) xenografts.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder using sterile PBS or 0.9% normal saline. |
| Storage | Store at 4°C for 2 years, do not freeze. |
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