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N6-methyladenosine (m6A) is a base modified analog of adenosine and is found as a minor nucleoside in natural RNAs. N6-Methyladenosine is an abundant modification in mRNA and is found within some viruses, and most eukaryotes including mammals, insects, plants and yeast. N6-Methyladenosine is a widespread RNA modification in many tissues with high levels in the brain. N6-Methyladenosine is enriched near stop codons and within 3’UTRs in both mouse and human mRNAs.
Adv Sci (Weinh). 2023 Jul 3;e2300892.
The Role of PRRC2B in Cerebral Vascular Remodeling Under Acute Hypoxia in Mice
N6-Methyladenosine purchased from AbMole
| Molecular Weight | 281.27 |
| Formula | C11H15N5O4 |
| CAS Number | 1867-73-8 |
| Solubility (25°C) | DMSO 36 mg/mL Water 14 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Wang X, et al. Nature. N6-methyladenosine-dependent regulation of messenger RNA stability.
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