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N6-Cyclopentyladenosine

Cat. No. M30066

All AbMole products are for research use only, cannot be used for human consumption.

N6-Cyclopentyladenosine Structure
Synonym:

CPA; UK-80882

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Quality Control & Documentation
Biological Activity

N6-Cyclopentyladenosine (CPA) is a selective Adenosine A1 receptor agonist, with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively.

Chemical Information
Molecular Weight 335.36
Formula C15H21N5O4
CAS Number 41552-82-3
Form Solid
Solubility (25°C) DMSO 12.5 mg/mL (ultrasonic)
Water 2.5 mg/mL (ultrasonic and warming and heat to 60°C)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jarogniew J Łuszczki, et al. Pharmacol Rep. 2-Chloro-N6-cyclopentyladenosine enhances the anticonvulsant action of carbamazepine in the mouse maximal electroshock-induced seizure model

[2] Milan Pospísil, et al. Eur J Pharmacol. N6-cyclopentyladenosine inhibits proliferation of murine haematopoietic progenitor cells in vivo

[3] B Schwierin, et al. Eur J Pharmacol. Effects of N6-cyclopentyladenosine and caffeine on sleep regulation in the rat

[4] M J Lohse, et al. Naunyn Schmiedebergs Arch Pharmacol. 2-Chloro-N6-cyclopentyladenosine: a highly selective agonist at A1 adenosine receptors

[5] H J Normile, et al. Brain Res Bull. N6-cyclopentyladenosine impairs passive avoidance retention by selective action at A1 receptors

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Keywords: N6-Cyclopentyladenosine, CPA; UK-80882 supplier, Adenosine Receptor, inhibitors, activators

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