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N3-PEG3-vc-PAB-MMAE is a synthesized drug-linker conjugate for ADC that incorporates the MMAE (a tubulin inhibitor ) and 3-unit PEG linker.
*The compound is unstable in solutions, freshly prepared is recommended
| Molecular Weight | 1352.66 |
| Formula | C67H109N13O16 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Drug-Linker Conjugates for ADC Products |
|---|
| Mc-Val-Cit-PABC-PNP
Mc-Val-Cit-PABC-PNP is a histone-cleavable peptide linker for antibody-drug couplings (ADCs) that can be used for the synthesis of ADCs such as Brentuximab vedotin. |
| DM1-SMCC
DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make ADC. |
| CL2A-SN-38
CL2A-SN-38 is a SN38 derivative with a peptide-linker which can easily react with antibody to form an ADC. |
| BS3 (bis(sulfosuccinimidyl)suberate)
BS3 (bis(sulfosuccinimidyl)suberate) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Sulfo-SMCC sodium
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. |
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