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N-(p-Coumaroyl) Serotonin

Cat. No. M39845

All AbMole products are for research use only, cannot be used for human consumption.

N-(p-Coumaroyl) Serotonin Structure

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Quality Control & Documentation
Biological Activity

N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca2+ release from sarcoplasmic reticulum. N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research.

Chemical Information
Molecular Weight 322.36
Formula C19H18N2O3
CAS Number 68573-24-0
Form Solid
Solubility (25°C) DMSO 150 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chan Hum Park et al. Am J Chin Med. Protective Effects of Serotonin and its Derivatives, N-Feruloylserotonin and N-(p-Coumaroyl) Serotonin, Against Cisplatin-Induced Renal Damage in Mice

[2] Michail Mitsis et al. J BUON. N-(p-coumaroyl) serotonin induces cell cycle arrest and apoptosis in breast cancer cells

[3] Diamanto Lazari et al. J Neurooncol. N-(p-coumaroyl) serotonin inhibits glioblastoma cells growth through triggering S-phase arrest and apoptosis

[4] Le-Le Zhang et al. Am J Chin Med. Phytochemistry and Pharmacology of Carthamus tinctorius L

[5] T Niwa et al. Biosci Biotechnol Biochem. Cis-N-(p-Coumaroyl)serotonin from Konnyaku, Amorphophallus konjac K. Koch

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Keywords: N-(p-Coumaroyl) Serotonin supplier, VEGFR/PDGFR, inhibitors, activators

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