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N-Octanoyl dopamine

Cat. No. M8520

All AbMole products are for research use only, cannot be used for human consumption.

N-Octanoyl dopamine Structure

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Biological Activity

N-Octanoyl dopamine (NOD) protects cell cultures and tissues from cold storage inflicted damage. N-Octanoyl dopamine decreases lactate-dehydrogenase (LDH) release during cold storage of cardiomyocytes in vitro. NOD did not induce a significant elevation of intracellular cAMP and is devoid of dopaminergic and adrenergic action.

Chemical Information
Molecular Weight 279.37
Formula C16H25NO3
CAS Number 105026-81-1
Solubility (25°C) DMSO: 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bjrn B Hofmann, et al. N-Octanoyl-Dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells

[2] Sivakkanan Loganathan, et al. N-octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors

[3] Rahel S Spindler, et al. N-Octanoyl Dopamine for Donor Treatment in a Brain-death Model of Kidney and Heart Transplantation

[4] Lamia Ait-Hsiko, et al. N-octanoyl-dopamine is a potent inhibitor of platelet function

[5] Charalambos Tsagogiorgas, et al. N-octanoyl-dopamine is an agonist at the capsaicin receptor TRPV1 and mitigates ischemia-induced [corrected] acute kidney injury in rat

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Keywords: N-Octanoyl dopamine supplier, inhibitors, activators

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