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N-Methylcytisine

Cat. No. M4371

All AbMole products are for research use only, cannot be used for human consumption.

N-Methylcytisine Structure
Size Price Availability Quantity
20mg USD 320 In stock
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Quality Control & Documentation
Biological Activity

N-methylcytisine (Caulophylline) is a tricyclic quinoline alkaloid with hypoglycemic, pain-relieving and anti-inflammatory activities. N-methylcytisine is a selective ligand of the acetylcholine acetylcholine receptor in the central nervous system and has a high affinity for the acetylcholine acetylcholine receptor in the optic ganglion of squid (Kd: 50 nM).

Chemical Information
Molecular Weight 204.27
Formula C12H16N2O
CAS Number 486-86-2
Form Solid
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Anna Petruczynik, et al. Determination of Cytisine and N-Methylcytisine from Selected Plant Extracts by High-Performance Liquid Chromatography and Comparison of Their Cytotoxic Activity

[2] Inna Tsypysheva, et al. Variation of spacer type and topology of phenyl moiety in 2-pyridone core of 4-oxo-3- N-methylcytisine; effect of synthesized compounds on rat's behavior in conditioned passive avoidance reflex (CPAR) test

[3] Yan-Fang Jiao, et al. N-Methylcytisine Ameliorates Dextran-Sulfate-Sodium-Induced Colitis in Mice by Inhibiting the Inflammatory Response

[4] Inna P Tsypysheva, et al. Anti-Inflammatory Activity of Novel 12-N-methylcytisine Derivatives

[5] Shuanghu Wang, et al. Determination of N-methylcytisine in rat plasma by UPLC-MS/MS and its application to pharmacokinetic study

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Keywords: N-Methylcytisine supplier, AChR/AChE, inhibitors, activators

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