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N-Ethylmaleimide (NEM) is a cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria.
Theranostics. 2020 Apr 27;10(13):5671-5686.
SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma
N-Ethylmaleimide purchased from AbMole
| Molecular Weight | 125.13 |
| Formula | C6H7NO2 |
| CAS Number | 128-53-0 |
| Solubility (25°C) | DMSO ≥ 25 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
| Related Cathepsin Products |
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| Odanacatib
Odanacatib (MK-0822) is a potent and reversible covalent inhibitor of CathepsinK (CatK) with an IC50 of 0.2 nM/1 nM for human/rabbit cathepsin B, L, and S and is highly selective. |
| Balicatib
Balicatib is a potent and selective inhibitor of cathepsin K; 10-100-fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S. |
| Aloxistatin
Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor. |
| Cathepsin Inhibitor 1
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. |
| Loxistatin Acid
Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor. |
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Products are for research use only. Not for human use. We do not sell to patients.
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