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Mycophenolate mofetil is an inhibitor of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil is also an immunosuppressive agent. Mycophenolate mofetil inhibits type 1 collagen expression and enhances MMP-1 expression. Mycophenolate mofetil reduces α-smooth muscle actin gene expression. The total area under the curve of Mycophenolate mofetil showed a 37% reduction in PPI patients vs those treated with no PPIs (P < 0.01), and the maximum peak concentration of Mycophenolate mofetil was 60% lower in the pantoprazole patients (P < 0.001).
| Molecular Weight | 433.49 |
| Formula | C23H31NO7 |
| CAS Number | 115007-34-6 |
| Solubility (25°C) | Soluble in acetone Soluble in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Allison AC, et al. Immunopharmacology. Mycophenolate mofetil and its mechanisms of action.
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