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Mupirocin is a natural crotonic acid derivative extracted from Pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial isoleucyl tRNA synthase. With excellent activity against gram-positive staphylococci and streptococci, it is primarily used for treatment of primary and secondary skin disorders, nasal infections, and wound healing. Mupirocin is a topically used antibiotic from a strain of Pseudomonas fluorescens. It has shown excellent activity against gram-positive staphylococci and streptococci. The antibiotic is used primarily for the treatment of primary and secondary skin disorders, nasal infections, and wound healing.
| Molecular Weight | 500.62 |
| Formula | C26H44O9 |
| CAS Number | 12650-69-0 |
| Solubility (25°C) | DMSO: 35 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Alexandra Tucaliuc, et al. Mupirocin: applications and production
[3] Jean B Patel, et al. Mupirocin resistance
[4] No authors listed. Drug Ther Bull. Mupirocin nasal ointment
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