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MST-312 is a chemically modified derivative of green tea epigallocatechin gallate (EGCG) and a telomerase inhibitor. It can be used in the study of tumors such as multiple myeloma (MM).1 μM MST-312 was shown to effectively reduce telomere length and inhibit proliferation in U937 cells.
| Molecular Weight | 380.35 |
| Formula | C20H16N2O6 |
| CAS Number | 368449-04-1 |
| Solubility (25°C) | DMSO: ≥20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Telomerase Products |
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| RHPS 4 methosulfate
RHPS 4 methosulfate is a telomerase inhibitor. RHPS 4 inhibits growth of medulloblastoma and glioblastoma cells in vitro. |
| Cycloastragenol
Cycloastragenol (Astramembrangenin) is the active form of Astragaloside IV and has antioxidant, anti-inflammatory, anti-aging, anti-apoptotic and cardiovascular protective effects. Cycloastragenol is an effective telomerase activator that lengthens telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties. |
| 360A iodide
360A iodide is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC50 of 300 nM for telomerase in TRAP-G4 assay. |
| Epitalon
Epitalon is an anti-aging agent and a telomerase activator. Epitalon has an inhibitory effect of the on the development of spontaneous tumors in mice, has geroprotective actions and intranasal administration increases neuronal activity. Epitalon can be used for cancer, old age and Retinitis Pigmentosa. |
| Ceramides
Ceramides, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides is a main lipid component of the permeability barrier in epidermis. |
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