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Roginolisib hemifumarate

Cat. No. M28709

All AbMole products are for research use only, cannot be used for human consumption.

Roginolisib hemifumarate Structure
Synonym:

MSC2360844 hemifumarate; IOA-244 hemifumarate

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Quality Control & Documentation
Biological Activity

Roginolisib (MSC2360844) hemifumarate is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib hemifumarate shows highly selective against a panel of 278 additional kinases.

Chemical Information
Molecular Weight 584.62
Formula C26H27FN4O5S.1/2C4H4O4
CAS Number 1621688-31-0
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage 4°C, dry, sealed
References

[1] Priyanka Kunamaneni, et al. Molecules. Aliskiren Hemifumarate Proliposomes for Improved Oral Drug Delivery: Formulation Development, In Vitro and In Vivo Permeability Testing

[2] M Gahr, et al. Pharmacopsychiatry. Aseptic gingivitis related to quetiapine hemifumarate

[3] En-Ju Wang, et al. Acta Crystallogr Sect E Struct Rep Online. rac-4-[4-Cyano-2-(hy-droxy-meth-yl)phen-yl]-4-(4-fluoro-phen-yl)-4-hy-droxy-N,N-dimethyl-butanaminium hemifumarate

[4] K Kappert, et al. Dtsch Med Wochenschr. [Aliskiren hemifumarate]

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  Catalog
Abmole Inhibitor Catalog




Keywords: Roginolisib hemifumarate, MSC2360844 hemifumarate; IOA-244 hemifumarate supplier, PI3K, inhibitors, activators

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