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MS31 

Cat. No. M29543

All AbMole products are for research use only, cannot be used for human consumption.

MS31  Structure

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Quality Control & Documentation
Biological Activity

MS31 is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 potently inhibits binding of trimethyllysine-containing peptides to SPIN1. MS31 is not toxic to nontumorigenic cells.

Chemical Information
Molecular Weight 341.45
Formula C20H27N3O2
CAS Number 2366264-12-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Pei-Tan Hsueh, et al. Trop Med Infect Dis. Transmission Modes of Melioidosis in Taiwan

[2] E Janet Tawn, et al. J Radiol Prot. Germline minisatellite mutations in workers occupationally exposed to radiation at the Sellafield nuclear facility

[3] A Uzura, et al. J Biosci Bioeng. Involvement of cytochrome P450 in hydroxylation of propylbenzene by Fusarium moniliforme strain MS31

[4] A Uzura, et al. J Biosci Bioeng. Conversion of various aromatic compounds by resting cells of Fusarium moniliforme strain MS31

[5] B Eriksen, et al. Int J Legal Med. DNA polymorphism in Greenland. Allele and profile frequencies in a Greenland population sample using the VNTR probes MS1, MS31, MS43a and YNH24

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  Catalog
Abmole Inhibitor Catalog




Keywords: MS31  supplier, Epigenetic Reader Domain, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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