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MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells.
| Molecular Weight | 565.71 |
| CAS Number | 2206736-04-9 |
| Solubility (25°C) | DMSO 55 mg/mL |
| Storage | -20°C, sealed |
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