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MRL-871 (compound 3) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 12.7 nM. MRL-871 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells.
| Molecular Weight | 444.79 |
| Formula | C22H12ClF3N2O3 |
| CAS Number | 1392809-08-3 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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