All AbMole products are for research use only, cannot be used for human consumption.
MPP+ iodide is a toxic metabolite of the neurotoxin MPTP, MPP+ iodide causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT). MPP+ also inhibits the activity of nicotinamide adenosine dinucleotide (NADH)-linked respiration in mitochondrial preparations and impairs aerobic glycolysis, leading to the present belief that the inhibition of NADH-linked cell respiration may constitute the final molecular mechanism of MPP+ neurotoxicity.
Mol Brain. 2025 Apr 04;18(1):29.
Target oxidative stress-induced disulfidptosis: novel therapeutic avenues in Parkinson’s disease
MPP+ iodide purchased from AbMole
Patent. CN119564831A 2025 Mar 07.
Patent. CN119564831A
MPP+ iodide purchased from AbMole
J Inflamm Res. 2024 May 21;17:3259-3282.
Role of Inflammation in the Development of COVID-19 to Parkinson’s Disease
MPP+ iodide purchased from AbMole
| Molecular Weight | 297.13 |
| Formula | C12H12IN |
| CAS Number | 36913-39-0 |
| Solubility (25°C) | Water 90 mg/mL DMSO 60 mg/mL |
| Storage | -20°C, dry, sealed |
| Related Animal Modeling Products |
|---|
| D-Galactosamine hydrochloride
D-Galactosamine hydrochloride is usually used with lipopolysaccharides (LPS) to induce models of acute hepatic failure (LPS/D-GalN-induced liver injury, hepatitis) for therapeutic research. |
| Doxorubicin HCL
Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. |
| Streptozotocin
Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended |
| Bleomycin sulfate
Bleomycin sulfate (Blenoxane) is a glycopeptide antitumor antibiotic isolated from Streptomyces verticillus. |
| Loperamide hydrochloride
Loperamide hydrochloride is a high affinity μ-opioid receptor agonist with peripheral selectivity with Ki values of 2, 48 and 1156 nM for μ-, δ- and κ-opioid receptors respectively. Loperamide hydrochloride is also a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. It can be used to construct animal models of functional constipation. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
