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MOPIPP is a novel indolebased chalcone, and vacuolin-1, is a non-lethal vacuoleinducing 2-propyl analog of MOMIPP. MOPIPP induces cellular vacuolization and increases autophagosomes numbers. MOPIPP also triggers methuosis, and interrupts glucose uptake and glycolytic metabolism. MOPIPP can cross the blood-brain barrier and shows efficacy in suppressing tumor progression agaisnt glioblastoma cells.
| Molecular Weight | 320.39 |
| Formula | C20H20N2O2 |
| CAS Number | 1485521-76-3 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] J Maphisa Maphisa. BJPsych Int. Mental health legislation in Botswana
[5] Girija S Singh. Mini Rev Med Chem. Synthetic Aziridines in Medicinal Chemistry: A Mini-Review
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