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MNK inhibitor 9 

Cat. No. M28995

All AbMole products are for research use only, cannot be used for human consumption.

MNK inhibitor 9  Structure

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Quality Control & Documentation
Biological Activity

MNK inhibitor 9 is a potent and selective inhibitor of MNK1/2 with IC50 values of 0.003 µM and 0.003 µM for MNK1 and MNK2 respectively. MNK inhibitor 9 has good cell permeability. MNK inhibitor 9 can be used in tumor related research.

Chemical Information
Molecular Weight 471.56
Formula C25H29N9O
CAS Number 1889336-59-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Carly Adamson, et al. Eur Heart J. Dapagliflozin for heart failure according to body mass index: the DELIVER trial

[2] Michael E Nassif, et al. Nat Med. The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

[3] Senthil Selvaraj, et al. Circulation. Metabolomic Profiling of the Effects of Dapagliflozin in Heart Failure With Reduced Ejection Fraction: DEFINE-HF

Related MNK Products
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CGP 57380 is potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.

Tomivosertib (eFT-508)

Tomivosertib (eFT-508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth.

SLV-2436

SLV-2436 (SEL201-88) is a novel ATP-competitive inhibitor of MNK1 and MNK2 with IC50 of 10.8 nM and 5.4 nM, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: MNK inhibitor 9  supplier, MNK, inhibitors, activators

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