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MM-401 is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 µM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia.
| Molecular Weight | 586.73 |
| Formula | C29H46N8O5 |
| CAS Number | 1442106-10-6 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Hui Zhang, et al. Bio Protoc. Reprogram Murine Epiblast Stem Cells by Epigenetic Inhibitors
[4] Masoud Vedadi, et al. Protein Sci. Targeting human SET1/MLL family of proteins
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Products are for research use only. Not for human use. We do not sell to patients.
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