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ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations.
| Molecular Weight | 508.63 |
| Formula | C27H32N4O4S |
| CAS Number | 850330-18-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 120 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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