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ML402, a thiophene-carboxamide, is a selective K2P2.1(TREK-1) and K2P10.1(TREK-2) activator. ML402 is inactive against K2P4.1(TRAAK).
| Molecular Weight | 295.78 |
| Formula | C14H14ClNO2S |
| CAS Number | 298684-44-3 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Lianne Pope, et al. Adv Exp Med Biol. The Polysite Pharmacology of TREK K2P Channels
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