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ML355 is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 0.34 μM, shows excellent selectivity over related lipoxygenases and cyclooxygenases, and possesses favorable ADME properties.
| Molecular Weight | 441.52 |
| CAS Number | 1532593-30-8 |
| Solubility (25°C) | DMSO ≥ 42 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Diane Luci, et al. Discovery of ML355, a Potent and Selective Inhibitor of Human 12-Lipoxygenase
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