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ML204 hydrochloride

Cat. No. M14282

All AbMole products are for research use only, cannot be used for human consumption.

ML204 hydrochloride Structure

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Quality Control & Documentation
Biological Activity

ML204 hydrochloride is a novel, potent, selective TRPC4/TRPC5 channel inhibitor, with at least 19-fold selectivity against TRPC6 and no appreciable effect on all other TRP channels, nor on voltage-gated sodium, potassium, or Ca2+ channels.

Chemical Information
Molecular Weight 262.78
CAS Number 2070015-10-8
Solubility (25°C) Water ≥ 30 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Alberto Arboit, et al. Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells

[2] Caoimhin S Griffin, et al. Muscarinic receptor-induced contractions of the detrusor are impaired in TRPC4 deficient mice

[3] J B Lindstrm, et al. Role of TRP Channels in Dinoflagellate Mechanotransduction

[4] Daria V Ilatovskaya, et al. The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling

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  Catalog
Abmole Inhibitor Catalog




Keywords: ML204 hydrochloride supplier, TRP Channel, inhibitors, activators

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