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ML188 is a first-in-class probe and also a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. antiviral activity.
| Molecular Weight | 433.54 |
| Formula | C26H31N3O3 |
| CAS Number | 1417700-13-0 |
| Form | Solid |
| Solubility (25°C) | DMSO >100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Jon Jacobs, et al. Discovery of non-covalent inhibitors of the SARS main proteinase 3CLpro
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