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ML-SI3 is a potent TRPML channel inhibitor with IC50s of 4.7 µM and 1.7 µM for TRPML1 and TRPML2, respectively.
| Molecular Weight | 429.58 |
| Formula | C23H31N3O3S |
| CAS Number | 891016-02-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 43 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Philip Schmiege, et al. Structure. Atomic insights into ML-SI3 mediated human TRPML1 inhibition
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