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ML 10302 hydrochloride is a potent 5-HT4 partial agonist (EC50 = 4 nM) that displays > 680-fold selectivity over 5-HT3 receptors (Ki values are 1.07 and 730 nM respectively). Increases sAPPα levels in the cortex in an animal model of Alzheimer's disease and exhibits progastrokinetic effects in vivo.
| Molecular Weight | 349.25 |
| Formula | C15H21ClN2O3.HCl |
| CAS Number | 186826-17-5 |
| Solubility (25°C) | DMSO 17.46 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Cohen, et al. TiBS. Okadaic acid: a new probe for the study of cellular regulation.
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