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MKT-077 (FJ-776) is a highly water-soluble mitochondrial dye (Ex/Em=488/543 nm). MKT-077 has significant antitumor activity, it exhibits low cytotoxicity, and inhibits broad-spectrum human cancer cell lines (colon cancer, breast cancer, pancreatic cancer).
| Molecular Weight | 432 |
| Formula | C21H22ClN3OS2 |
| CAS Number | 147366-41-4 |
| Solubility (25°C) | DMSO 46 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Macaluso, et al. ChemMedChem. Discovery of a competitive apelin receptor (APJ) antagonist.
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