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MK6-83 is an agonist of the transient receptor potential channel ML3 (TRPML3). MK6-83 appears to be significantly more efficacious on fibroblast lysosomes isolated from R403C or V446L expressing cells than on those isolated from TRPML1-/- cells.
Traffic. 2022 May;23(5):238-269.
Current methods to analyze lysosome morphology, positioning, motility and function
MK6-83 purchased from AbMole
| Molecular Weight | 336.46 |
| Formula | C16H20N2O2S2 |
| CAS Number | 1062271-24-2 |
| Solubility (25°C) | DMSO 4 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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