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MK-4541 

Cat. No. M30623

All AbMole products are for research use only, cannot be used for human consumption.

MK-4541  Structure

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Quality Control & Documentation
Biological Activity

MK-4541 is an orally active and selective androgen receptor (AR) modulator. MK-4541 acts as an antagonist to inhibit 5α-reductase. MK-4541 inhibits proliferation and induces apoptosis in AR positive prostate cancer cells. MK-4541 significantly inhibited the growth of R3327-G prostate tumors in xenograft mouse model.

Chemical Information
Molecular Weight 428.49
Formula C22H31F3N2O3
CAS Number 796885-38-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Michael J Chisamore, et al. J Steroid Biochem Mol Biol. A novel selective androgen receptor modulator (SARM) MK-4541 exerts anti-androgenic activity in the prostate cancer xenograft R-3327G and anabolic activity on skeletal muscle mass & function in castrated mice

[2] Azriel Schmidt, et al. J Steroid Biochem Mol Biol. Identification of an anabolic selective androgen receptor modulator that actively induces death of androgen-independent prostate cancer cells

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  Catalog
Abmole Inhibitor Catalog




Keywords: MK-4541  supplier, Androgen Receptor, inhibitors, activators

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