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MK-0941 free base is an orally active glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 free base exhibits strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes.
| Molecular Weight | 460.5 |
| Formula | C21H24N4O6S |
| CAS Number | 752240-01-0 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Related Glucokinase (GK) Products |
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| LY2608204
LY2608204 activates glucokinase (GK) with EC50 of 42 nM. |
| AM2394
AM-2394 is a structurally distinct glucokinase activator (GKA). AM-2394 activates glucokinase (GK) with an EC50 of 60 nM. |
| Dorzagliatin
Dorzagliatin (HMS-5552, RO-5305552, Sinogliatin) is a glucokinase (GK) activator, which improves glycaemic control and pancreatic β-cell function for type 2 diabetes. |
| AZD1656
AZD1656 is a potent, selective and orally active glucokinase (GK) activator, with an EC50 of 60 nM. |
| Cadisegliatin (TTP-399)
Cadisegliatin (TTP-399) is a potential, orally active liver-selective glucokinase (GK) activator. Cadisegliatin has antihyperglycaemic activity. Cadisegliatin can be used for the research of type 2 diabetes. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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