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MitoTracker Red CMXRos

Cat. No. M19979

All AbMole products are for research use only, cannot be used for human consumption.

MitoTracker Red CMXRos Structure
Synonym:

Chloromethyl-X-rosamine

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50ug USD 100 In stock
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Biological Activity

Mitotracker red cmxros is a red fluorescent dye used for staining mitochondria of living cells. Mitotracker red cmxros is a cell permeable x-rosamine derivative containing a weakly thiol reactive chloromethyl functional group that marks mitochondria. The maximum excitation / emission wavelength is 579 / 599nm- At 20 ℃, it shall be sealed and dried in a dark and moisture-proof manner. This product is an oxidized red fluorescent dye. It can be passively transported through the cell membrane and directly accumulated on the active mitochondria by simply incubating the cells. The accumulation of this dye depends on the membrane potential. Once the mitochondria are stained, they can also be fixed (aldehyde fixative such as formaldehyde) and permeabilized (aldehyde detergent such as Triton X-100) according to the needs of subsequent experiments, and the probe is still maintained in the cell. Because the red fluorescence of mitotracker red cmxros has good resolution with other green fluorescence probes, this product is suitable for double standard experiments.

Product Citations
Chemical Information
Molecular Weight 531.5236
Formula C32H32Cl2N2O
CAS Number 167095-09-2
Solubility (25°C) Soluble in DMSO
Storage -20°C, protect from light, dry, sealed
References

[1] Tianyi Ma, et al. Oxid Med Cell Longev. SFRP2 Improves Mitochondrial Dynamics and Mitochondrial Biogenesis, Oxidative Stress, and Apoptosis in Diabetic Cardiomyopathy

[2] Xinyi Lu, et al. Autophagy. AMPK protects against alcohol-induced liver injury through UQCRC2 to up-regulate mitophagy

[3] Daniel Puleston. Cold Spring Harb Protoc. Detection of Mitochondrial Mass, Damage, and Reactive Oxygen Species by Flow Cytometry

[4] Prajakta S Jogdand, et al. Malar J. Flow cytometric readout based on Mitotracker Red CMXRos staining of live asexual blood stage malarial parasites reliably assesses antibody dependent cellular inhibition

[5] W Pendergrass, et al. Cytometry A. Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues

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Keywords: MitoTracker Red CMXRos, Chloromethyl-X-rosamine supplier, Fluorescent Dye, inhibitors, activators

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