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Mitotane is an isomer of DDD and a derivative of DDT that induces CYP3A4 gene expression through steroid and exogenous receptor (SXR) activation, and has anticancer activity, and may be used in studies related to adrenocortical carcinoma.
| Molecular Weight | 320.04 |
| Formula | C14H10Cl4 |
| CAS Number | 53-19-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] U Waszut, et al. Understanding mitotane mode of action
[5] Stefanie Hahner, et al. Mitotane for adrenocortical carcinoma treatment
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