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(±)-Praeruptorin A

Cat. No. M4485

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(±)-Praeruptorin A Structure
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20mg USD 200 In stock
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Biological Activity

(±)-Praeruptorin A is A diesterification product of cis-lactone (CKL), and is the main active component of Peucedani Radix composed of dried Peucedanum praeruptorumDunn. (±)-Praeruptorin A has been widely used as one of the traditional Chinese medicines to study cough with thick sputum and dyspnea, non-natural cough and upper respiratory tract infection. (±)-Praeruptorin A can be used as A Ca2+- reflux blocker in the study of hypertension.

Chemical Information
Molecular Weight 386.40
Formula C21H22O7
CAS Number 73069-25-7
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, sealed
References

[1] Chen-Lin Yu, et al. Praeruptorin A reduces metastasis of human hepatocellular carcinoma cells by targeting ERK/MMP1 signaling pathway

[2] Yijuan Hu, et al. Rapid and Simultaneous Measurement of Praeruptorin A, Praeruptorin B, Praeruptorin E, and Moisture Contents in Peucedani Radix Using Near-Infrared Spectroscopy and Chemometrics

[3] Jeong-Tae Yeon, et al. Praeruptorin A inhibits in vitro migration of preosteoclasts and in vivo bone erosion, possibly due to its potential to target calmodulin

[4] Xunian Zhou, et al. Effects of praeruptorin A and praeruptorin C, a racemate isolated from Peucedanum praeruptorum, on MRP2 through the CAR pathway

[5] Zhao Xu, et al. (+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis

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Keywords: (±)-Praeruptorin A supplier, Calcium Channel, inhibitors, activators

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