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(-)-Maackiain

Cat. No. M4583

All AbMole products are for research use only, cannot be used for human consumption.

(-)-Maackiain Structure
Synonym:

l-Maackiain

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20mg USD 250 In stock
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Biological Activity

Maackiain (DL-Maackiain) was separated from Maackia amurensis Rupr. Et Maxim. Maackiain (DL-Maackiain) is a larval insecticide against Aedes aegypti with a LD50 of 21.95 μg/ mL. Maackiain (DL-Maackiain) induces DNA fragmentation into oligonucleosome size fragments, similar to apoptotic characteristics such as HL-60 cells.

Chemical Information
Molecular Weight 284.26
Formula C16H12O5
CAS Number 19908-48-6
Form Solid
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Wen-Lin Yuan, et al. Metabolites and metabolic pathways of maackiain in rats based on UPLC-Q-TOF-MS

[2] Jiahong Guo, et al. Maackiain Protects the Kidneys of Type 2 Diabetic Rats via Modulating the Nrf2/HO-1 and TLR4/NF-κB/Caspase-3 Pathways

[3] Yuhao Liu, et al. Maackiain dampens osteoclastogenesis via attenuating RANKL-stimulated NF-κB signalling pathway and NFATc1 activity

[4] Rong-Tzong Tsai, et al. Maackiain Ameliorates 6-Hydroxydopamine and SNCA Pathologies by Modulating the PINK1/Parkin Pathway in Models of Parkinson's Disease in Caenorhabditis elegans and the SH-SY5Y Cell Line

[5] Jin-Won Huh, et al. Maackiain, a compound derived from Sophora flavescens, increases IL-1β production by amplifying nigericin-mediated inflammasome activation

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Keywords: (-)-Maackiain, l-Maackiain supplier, Parasite, inhibitors, activators

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