(-)-Curine

Cat. No. M38968

All AbMole products are for research use only, cannot be used for human consumption.

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Quality Control & Documentation

Purity: >98.0%
COA
MSDS

Product Information

Biological Activity

(-)-Curine is an orally active bisbenzylisoquinoline alkaloid isolated from Chondrodendron platyphyllum. (-)-Curine presents anti-inflammatory and analgesic effects at nontoxic doses, at least in part, resulting from the inhibition of prostaglandin E2 production.

Chemical Information

Molecular Weight	594.7
Formula	C36H38N2O6
CAS Number	436-05-5
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Jaime Ribeiro-Filho et al. Toxins (Basel). Curine Inhibits Macrophage Activation and Neutrophil Recruitment in a Mouse Model of Lipopolysaccharide-Induced Inflammation

[2] Jaime Ribeiro-Filho et al. Molecules. Anti-allergic properties of curine, a bisbenzylisoquinoline alkaloid

[3] Fagner Carvalho Leite et al. Planta Med. Curine, an alkaloid isolated from Chondrodendron platyphyllum inhibits prostaglandin E2 in experimental models of inflammation and pain

[4] Jaime Ribeiro-Filho et al. J Ethnopharmacol. Curine inhibits mast cell-dependent responses in mice

[5] Jaime Ribeiro-Filho et al. Toxicol Appl Pharmacol. Curine inhibits eosinophil activation and airway hyper-responsiveness in a mouse model of allergic asthma

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(-)-Curine

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