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Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect.
| Molecular Weight | 457.48 |
| Formula | C23H27N3O7 |
| CAS Number | 10118-90-8 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] Sher Singh, et al. Curr Mol Pharmacol. Minocycline and Doxycycline: More Than Antibiotics
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
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