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Minnelide

Cat. No. M28054

All AbMole products are for research use only, cannot be used for human consumption.

Minnelide Structure
Size Price Availability
2mg USD 160 4-7 Days
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Quality Control & Documentation
Biological Activity

Minnelide is a precursor of triptolide that shows potent antitumor activity in a number of tumor types, particularly in pancreatic cancer. Minnelide promotes apoptosis.

Chemical Information
Molecular Weight 514.37
Formula C21H25Na2O10P
CAS Number 1254702-87-8
Form Solid
Solubility (25°C) Water 93.33 mg/mL (ultrasonic)
DMSO 16.67 mg/mL (ultrasonic)
Storage 4°C, sealed
References

[1] Shrey Modi, et al. Cancer Lett. Minnelide synergizes with conventional chemotherapy by targeting both cancer and associated stroma components in pancreatic cancer

[2] Vivek Ramakrishnan, et al. Am J Cancer Res. Minnelide, a prodrug, inhibits cervical cancer growth by blocking HPV-induced changes in p53 and pRb

[3] Pawan Noel, et al. Trends Pharmacol Sci. Triptolide and Its Derivatives as Cancer Therapies

[4] Sulagna Banerjee, et al. Pancreatology. Minnelide, a novel drug for pancreatic and liver cancer

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Keywords: Minnelide supplier, Apoptosis, inhibitors, activators

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